Arsenal have to wait for a place in the knockout stages of the Europa League after losing at home to Eintracht Frankfurt at a half-empty Emirates, while Wolverhampton Wanderers, Braga, Vfl Wolfsburg, Sporting and AZ Alkmaar all advanced.
Gent, LASK and Apoel Nicosia also reached the last 32 but Arsenal’s woes continued as Frankfurt’s Daichi Kamada scored twice to secure a 2-1 win over Unai Emery’s team in their Group F clash on a night when places in the last 32 were up for grabs.
The North London side are still likely to go through but won’t be able to confirm their spot until their last game at Belgian side Standard Liege, who drew 1-1 at Vitoria SC.
Arsenal had taken the lead in the first half through Pierre-Emerick Aubameyang, but Japanese midfielder Kamada’s double after the break increased the pressure on under-fire Emery.
Sporting had no such problems as they hammered visiting PSV Eindhoven 4-0 to qualify from Group D and will be joined by LASK of Austria who beat Norwegians Rosenborg 2-1 in Trondheim.
Apoel Nicosia cruised to a 2-0 win at Dudelange and got a helping hand from Group A winners Sevilla, who beat Qarabag by the same scoreline to put the Cypriots through as runners-up.
Lazio got the 1-0 win they needed over CFR Cluj to keep their hopes alive, while Scottish champions Celtic secured top spot in Group E with a 3-1 win at home to Stade Rennes.
Group B is still up for grabs after FC Copenhagen eliminated Lugano with a 1-0 away win and Malmo beat Dynamo Kiev 4-3 with a last-gasp Markus Rosenberg goal as the 37-year-old scored his second goal of the night in his last home game for the club.
In the early games, Wolverhampton Wanderers and Braga played out a thrilling 3-3 draw to book their last-32 spots.
Ten-man Alkmaar had substitute Ferdy Druijf to thank for two late goals as they recovered to draw 2-2 at home to Partizan Belgrade in Group L and join leaders Manchester United, whose second-string side lost 2-1 at Astana, in the knockout phase.
AS Roma boosted their hopes of qualifying from Group J by winning 3-0 at Istanbul Basaksehir with first-half goals from Jordan Veretout, Justin Kluivert and Eden Dzeko, while Borussia Moenchendgladbach went top with a 1-0 win at Wolfsberger AC.
In Group G, Porto grabbed a lifeline with a 2-1 away win over Swiss side Young Boys to keep themselves in contention, while Scottish side Rangers moved into first place on eight points with a gritty 2-2 draw at Feyenoord.